Chebulinic acid NEW
| Price | $64 | $156 | $226 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-13 |
Product Details
| Product Name: Chebulinic acid | CAS No.: 18942-26-2 |
| Purity: 99.54% | Supply Ability: 10g |
| Release date: 2026/05/13 |
Product Introduction
Bioactivity
| Name | Chebulinic acid |
| Description | Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity. |
| In vitro | Chebulinic acid obviously inhibited HQ/Cu(II)- and H(2)O(2)/Cu(II)-mediated pBR322 DNA strand breaks. When MRC-5 cells were treated with HQ/Cu(II), the presence of Chebulinic acid inhibited HQ/Cu(II)-mediated double-strand breaks of genomic DNA [1]. |
| In vivo | Chebulinic acid had no effect on KCl-induced aortic contraction, but irreversibly inhibited the contractile responses to phenylephrine in an apparently non-competitive manner. Chebulinic acid also inhibited contractile responses of rat aorta to 5-hydroxytryptamine and angiotensin II. 3. Chebulinic acid inhibited the binding of [3H]-prazosin to dog aortic microsomal membranes in a concentration-dependent manner with an IC50 value of 0.34 mmol/L [2]. |
| Storage | Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : <1 mg/mL (insoluble) DMSO : 130 mg/mL (135.89 mM), Sonication is recommended. |
| Keywords | Transforming growth factor beta | TGF-β/Smad | TGFβ | TGF-beta/Smad | TGFbeta/Smad | TGF-beta | TGFbeta | TGF-b/Smad | TGFb | Smad3 | Smad | RNASynthesis | RNA Synthesis | Protonpump | Proton pump | Inhibitor | inhibit | H+/K+-ATPase | DNASynthesis | DNA/RNA Synthesis | DNA Synthesis | Chebulinic acid | bacterial DNA gyrase |
| Inhibitors Related | Neomycin sulfate | Levulinic acid | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Thymidine | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | TGF-beta/Smad Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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