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Postion:Product Catalog >API>Antineoplastic agents>Antibiotics anticancer drugs>Chromomycin A3
Chromomycin A3
  • Chromomycin A3

Chromomycin A3 NEW

Price $178 $490 $888
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-24

Product Details

Product Name: Chromomycin A3 CAS No.: 7059-24-7
Supply Ability: 10g Release date: 2026/04/24

Product Introduction

Bioactivity

NameChromomycin A3
DescriptionChromomycin A3 is an antibiotic produced by Streptomyces sp that binds to gc-rich DNA sequences in the presence of divalent cations and inhibits DNA replication and transcription; it is also used as a fluorescent DNA stain and assay; and it has anticancer activity against diseases such as Hodgkin's, lung adenocarcinomas, melanomas, and breast cancer.
In vitroChromomycin A3 showed strong antiproliferative effects in human pancreatic cancer cells AsPC-1, MIA PaCa-2, and BxPC-3 (IC??: 2.01, 1.34, and 1.15 nM, respectively; 72 h treatment), and induced apoptosis at 5 nM with increased cleaved caspase-3 and PARP[1].
In vivoIn a MIA PaCa-2 xenograft model, intraperitoneal injection of Chromomycin A3 (0.5 mg/kg, once daily for 14 days) reduced tumor volume by over 60% without notable toxicity; tumor tissues showed reduced Ki-67 and increased cleaved caspase-3[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 80 mg/mL (67.61 mM), Sonication is recommended.
KeywordsChromomycin A-3 | Chromomycin A3
Inhibitors RelatedNeomycin sulfate | Calcium Propionate | Aceglutamide | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Sulfamethoxazole sodium | Formamide | Thymidine | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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