Cirazoline hydrochloride NEW
| Price | $359 | $533 | $759 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: Cirazoline hydrochloride | CAS No.: 40600-13-3 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | Cirazoline hydrochloride |
| Description | Cirazoline hydrochloride is a synthetic compound that acts as a competitive full agonist of the α1A-adrenergic receptor (α1A-AR) with a binding affinity of Ki = 120 nM, and Cirazoline hydrochloride also functions as a partial agonist at α1B-AR (Ki = 960 nM) and α1D-AR (Ki = 660 nM), thereby serving as a versatile adrenergic receptor probe with relevance for studying vascular tone regulation, adrenergic pharmacology, and potential therapeutic cardiovascular applications. |
| In vitro | Methods: Glioblastoma-initiating cells were treated with cirazoline hydrochloride (5-10 μM, 24 hours), and cell viability was measured using the WST-1 reduction assay. Results: Cirazoline hydrochloride did not alter the viability of GICs and only slightly antagonized prazosin-induced GIC death. [2] |
| In vivo | Methods: B6/CBA mice were treated with Cirazoline hydrochloride (drinking water, 40 μM, for 9 months) to investigate the influence of α1A-AR signaling in antidepressant effects. Results: Wild-type mice with long-term intake of Cirazoline hydrochloride showed a significant reduction in immobility time during the TST (tail suspension test). [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 24 mg/mL (94.96 mM), Sonication is recommended. |
| Keywords | LD-3098 Hydrochloride | Cirazoline Hydrochloride |
| Inhibitors Related | Theophylline monohydrate | Octopamine hydrochloride | Inosine | Dexmedetomidine hydrochloride | Theobromine | Isoprenaline hydrochloride | D-Mannitol | Mianserin hydrochloride | Trazodone hydrochloride | Theophylline | Doxofylline | Doxepin hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | ReFRAME Related Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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