CL-82198 NEW
| Price | $40 | $93 | $153 |
| Package | 10mg | 25mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-08 |
Product Details
| Product Name: CL-82198 | CAS No.: 307002-71-7 |
| Purity: 95.91% | Supply Ability: 10g |
| Release date: 2026/06/08 |
Product Introduction
Bioactivity
| Name | CL-82198 |
| Description | CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA). Its mechanism of action involves binding to the S1' pocket of MMP-13, ensuring its selectivity and preventing inhibition of other MMPs. |
| In vitro | CL-82198 decreases CTGF and TGF-β1 protein levels in hepatic stellate cells[3]. CL-82198 (10 μM; 24 hours) obviously reduces LS174 cell migration[1]. |
| In vivo | CL82198 (1-10 mg/kg; i.p.; every other day for 12 weeks) treatment avoids and decelerates MLI-induced osteoarthritis progression. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (13.23 mM), Sonication is recommended. DMSO : 100 mg/mL (330.72 mM), Sonication is recommended. |
| Keywords | MMP-13 | MMP | Matrix metalloproteinases | Inhibitor | inhibit | CL-82198 | CL82198 | CL 82198 |
| Inhibitors Related | Rhamnose monohydrate | Doxycycline (hyclate) | Chondroitin sulfate | Astragaloside IV | Doxycycline | Edaravone | Glucosamine | Anethole | Meloxicam | Chloramphenicol | Propoxur | Methylchloroisothiazolinone/Methylisothiazolinone Mixture |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Protease Inhibitor Library | Angiogenesis related Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Fibrosis Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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