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Postion:Product Catalog >API>Antibiotics>Lincosamides Drugs>Clindamycin phosphate
Clindamycin phosphate
  • Clindamycin phosphate
  • Clindamycin phosphate
  • Clindamycin phosphate
  • Clindamycin phosphate
  • Clindamycin phosphate

Clindamycin phosphate NEW

Price Get Latest Price
Package 1kg 25kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2026-06-08

Product Details

Product Name: Clindamycin phosphate CAS No.: 24729-96-2
EC-No.: 246-433-0 Min. Order: 1kg
Purity: 99% Supply Ability: 100kg
Release date: 2026/06/08

Items

Specifications

Results

Appearance

White   to off-white crystalline powder

White crystalline powder

Identification

IR:Meets   the requirements

Conform

HPLC:retention   time conforms to RS

Conform

Crystallinity

Conform

Conform

PH

3.5~4.5

4.0

Water

≤   6.0%

0.41%

Assay

≥758μg/mg   clindamycin on the anhydrous substance

836μg/mg

Organic   Impurities

Lincomycin   phosphate  ≤1.0%

0.049%

Lincomycin    ≤0.5%

N.D.

Clindamycin   B phosphate   ≤1.5%

0.053%

7-Epiclindamycin   phosphate  ≤0.8%

0.21%

Clindamycin   3-phosphate  ≤0.3%

N.D.

Clindamycin    ≤0.5%

N.D.

Any   indivdual,unspecified impurity  ≤1.0%

N.D.

Total   impurities   ≤4.0%

0.31%

Residual solvents

Methanol   ≤3000ppm

0.3


 Ethanol      ≤5000ppm

580ppm


Acetone    ≤5000ppm

N.D.

Conclusion

The product conforms to the   above specifications.

Clindamycin Phosphate: Overview & Uses

Clindamycin phosphate is a water-soluble prodrug ester of the antibiotic clindamycin. It is inactive until converted by enzymes in the body into biologically active clindamycin.

  • Class: Lincosamide antibiotic.

    Key Advantage: The phosphate ester form allows for parenteral administration (injection) and topical formulation, as it is much more soluble than clindamycin base.

Mechanism of Action

Once converted to active clindamycin, it works by binding to the 50S subunit of the bacterial ribosome. This inhibits bacterial protein synthesis, preventing bacteria from growing and multiplying (it is primarily bacteriostatic).

Primary Uses & Applications

1. Topical Formulations (Most Common Use):

  • Acne Vulgaris: A first-line topical treatment for inflammatory acne (gels, lotions, foams). Often combined with benzoyl peroxide.

    Bacterial Vaginitis: Used as a vaginal cream or suppository.

    Skin Infections: Topical solutions for minor bacterial skin infections.

2. Parenteral (Injectable) Formulations:
Used for serious systemic infections caused by anaerobic bacteria and certain gram-positive aerobes, including:

  • Severe Skin & Soft Tissue Infections (e.g., abscesses, cellulitis).

    Intra-abdominal Infections (often mixed anaerobic/aerobic).

    Pelvic Inflammatory Disease (PID).

    Bone & Joint Infections.

    As an alternative for patients allergic to penicillin.

3. Oral Form (Clindamycin HCl):
For similar systemic infections when oral therapy is appropriate.

Important Warnings & Side Effects

  • Clostridioides difficile-Associated Diarrhea (CDAD): A major risk. Can cause severe, potentially fatal colitis. Use is reserved for cases where benefits outweigh risks.

    Allergy: Contraindicated in patients with hypersensitivity to clindamycin or lincomycin.

    Spectrum: Primarily targets anaerobic bacteria and gram-positive cocci (e.g., Staphylococcus aureus, streptococci). NOT effective against gram-negative bacilli.

    Prescription Only: Requires medical supervision.

Key Summary Table

FeatureDescription
What it isA soluble prodrug of the antibiotic clindamycin.
Main MechanismInhibits bacterial protein synthesis (bacteriostatic).
Topical UsesAcne vulgaris, bacterial vaginosis, minor skin infections.
Systemic (IV/IM/Oral) UsesSerious anaerobic & gram-positive infections (skin, abdomen, bone, pelvis).
Critical WarningHigh risk of causing C. difficile colitis (severe diarrhea).
AvailabilityPrescription-only, in topical (gel, lotion, cream), vaginal, and injectable forms.

Disclaimer: This information is for educational purposes. Clindamycin is a potent antibiotic with significant risks and must be used only under the direction of a healthcare professional.

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Article illustration

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Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber. Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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  • Since: 2006-04-03
  • Address: Room 2015, No.2 Building Kaixin Mansion, No.107 Jinqiao Ave, Wuhan, China
INQUIRY
Betty Shu

info@fortunachem.com
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