Clobutinol NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: Clobutinol | CAS No.: 14860-49-2 |
| Supply Ability: 10g | Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | Clobutinol |
| Description | Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3]. |
| In vitro | Clobutinol markedly suppresses the voltage-gated outward current in cells expressing hERG at a concentration of 10 μM [1]. Furthermore, in hERG transfected cells, clobutinol (0-1000 μM) inhibits this outward current, demonstrating an IC 50 value of 1.9 μM [1]. |
| In vivo | Clobutinol, administered intravenously at doses ranging from 1-20 mg/kg, was found to have no significant impact on the airways of anesthetized guinea pigs. However, at doses of 1 and 10 mg/kg, clobutinol influenced the cardiovascular system, notably decreasing heart rate and mean blood pressure in anesthetized closed-chest guinea pigs. This effect was more pronounced with the higher dosage of 10 mg/kg, indicating a dose-dependent response on cardiovascular parameters without affecting the respiratory system. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Minoxidil sulfate | Uridine 5'-monophosphate disodium salt | Tannic acid | Hydrochlorothiazide | 1,8-Cineole | Tetraethylammonium bromide | Ursodeoxycholic acid | Chenodeoxycholic acid | Minoxidil | 2,2,2-Trichloroethanol | Chlorzoxazone | Indapamide |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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