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Postion:Product Catalog >Biochemical Engineering>Inhibitors>COH34
COH34
  • COH34

COH34 NEW

Price $66 $158 $248
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: COH34 CAS No.: 906439-72-3
Purity: 99.57% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameCOH34
DescriptionCOH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
In vitroCOH34 potently inhibits PARP inhibitor-resistant cancer cells[1].
In vivoCOH34 shows antitumor activity in xenograft mouse cancer models[1].
StorageStore at low temperature Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (3.41 mM), Sonication is recommended.
10% DMSO+90% Saline : 4 mg/mL (13.63 mM), Suspension.
DMSO : 40 mg/mL (136.34 mM), Sonication is recommended.
KeywordsPARG | COH-34 | COH34 | COH 34
Inhibitors RelatedEthacridine | PDD00017272 | JA2131 | PARP-1-IN-32 | TFMU-ADPr triethylamine | COH34 analog 1 | PDD00017238 | Endo-1,4-β-xylanase | pNP-ADPr | PARG-IN-4 | pNP-ADPr disodium | PDD00017273

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

Product name Price   Suppliers Update time
$30.00
VIP6Y
TargetMol Chemicals Inc.
2026-05-09
$66.00
VIP6Y
TargetMol Chemicals Inc.
2026-06-02

TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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