Colcemid NEW
| Price | $31 | $98 | $156 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-15 |
Product Details
| Product Name: Colcemid | CAS No.: 477-30-5 |
| Purity: 99.65% | Supply Ability: 10g |
| Release date: 2026/05/15 |
Product Introduction
Bioactivity
| Name | Colcemid |
| Description | Colcemid (NSC-3096) is a microtubule polymerization inhibitor that primarily targets tubulin, with an IC?? of 2.4 μM. Demecolcine interacts with tubulin dimers, induces antimitotic effects, and inhibits microtubule growth. Colcemid is a classic reagent used in karyotyping, banding techniques, and cell cycle synchronization. Colcemid can induce apoptosis and is used in studies of tumor and embryonic cloning. |
| In vitro | Methods: In a co-culture system of neonatal rat cardiomyocytes (CM) and myofibroblasts (MF), mitochondria were labeled with Ad-Mito-EGFP. After 4-hour treatment with Colcemid (4 μM), live cells were tracked in real-time using confocal microscopy to monitor mitochondrial movement within MNTs, and migration velocity was calculated. Results: Colcemid treatment significantly reduced mitochondrial migration speed within MNTs but did not affect MNT formation. [1] |
| Storage | Keep away from moisture,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 55 mg/mL (148.08 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.38 mM), Sonication is recommended. |
| Keywords | tumor | NSC3096 | NSC 3096 | mitotic | MicrotubuleAssociated | Microtubule/Tubulin | Microtubule Associated | metaphase | Inhibitor | inhibit | derivative | Colcemid | cancer | apoptosis |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Rare Natural Product Library | Alkaloid Natural Product Library | Selected Plant-Sourced Compound Library | Microtubule-Targeted Compound Library | Inhibitor Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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