Product Details
| Product Name:
Coumarin343 |
CAS No.:
55804-65-4 |
| Purity:
97.74% |
Supply Ability:
10g |
| Release date:
2026/04/27 |
Product Introduction
Bioactivity
| Name | Coumarin343 |
| Description | Coumarin343 inhibits monocarboxylic acid transporter protein 4 with IC50 values in the range of 0.01-100 μM.Coumarin343 exhibits anticancer and antibacterial activity.Coumarin343 is a coumarin dye. |
| Cell Research | As an MCT4 inhibitor
1. Dissolution: Coumarin 343 can be dissolved in organic solvents such as DMSO or ethanol with good solubility. The specific solubility and solvent selection depend on the experimental conditions.
2. IC50 concentration: In the experiment of inhibiting MCT4, the concentration range of Coumarin 343 is usually 0.01-100 μM, and the specific concentration is optimized according to the experimental design.
3. Cell treatment: In the cell model, different concentrations of Coumarin 343 are added to the culture medium to observe its inhibitory effect on MCT4 function. Changes in MCT4 protein or RNA can be detected by Western blot, RT-PCR and other techniques.
II. Application of anticancer and antibacterial activity:
Coumarin 343 has certain anticancer activity in cancer cells, which can act by affecting the metabolic pathways of cancer cells or by direct cytotoxic effects.
Its antibacterial activity also makes it useful in the study of infectious diseases, especially in the potential to inhibit the growth of certain bacteria.
3. Fluorescence labeling and imaging:
When used, Coumarin 343 can be dissolved in DMSO or PBS and added to the cell culture medium for staining, usually for 15-30 minutes.
The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 4.23 mg/mL (14.83 mM), Sonication is recommended.
|
| Keywords | Monocarboxylatetransporter | Monocarboxylate transporter | Bacterial |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
| Related Compound Libraries | Bioactive Compound Library | Anti-Bacterial Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Infection Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$7.00
|
VIP8Y
|
Career Henan Chemical Co
|
2019-09-02 |
United States