Factory Provide Liver Disease Medication CAS 60-27-5 Creatinine Powder

Introduction

Product Name : Creatinine

Other name:2-IMINO-1-METHYLIMIDAZOLIDIN-4-ONE;2-IMINO-N-METHYLHYDANTOIN;KREATININ;METHYLGUANIDINEACETIC ACID

CAS No.: 60-27-5

MF:C4H7N3O

MW:113.12

Appearance: White Powder

Melting Point :295 °C (dec.) (lit.)

Boiling Point :211.83°C (rough estimate)

Density :1.2526 (rough estimate)

Storage :Keep in dark place,Sealed in dry,Room Temperature

Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.Target: OthersCreatinine is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass). Creatine is synthesized primarily in the liver from the methylation of glycocyamine (guanidino acetate, synthesized in the kidney from the amino acids arginine and glycine) by S-adenosyl methionine. It is then transported through blood to the other organs, muscle, and brain, where, through phosphorylation, it becomes the high-energy compound phosphocreatine. During the reaction, creatine and phosphocreatine are catalyzed by creatine kinase, and a spontaneous conversion to creatinine may occur. Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function.

Application of Creatinine 

1. Creatine anhydrous is a colorless, crystalline substance used in muscle tissue for the production of phosphocreatine
2.Creatine anhydrous is an important factor in the formation of adenosine triphosphate triphosphate(ATP), the source of energy for muscle contraction and many other functions in the body.
3.Creatine supplements are sometimes used by athletes, bodybuilders, wrestlers and others who wish to gain muscle mass, typically consuming 2 to 3 times the amount that could be obtained from a very-high-protein diet.

Function of Creatinine

1. Creatinine is a chemical waste molecule that is generated from muscle metabolism.
2. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles.

3. Approximately 2% of the body's creatine is converted to creatinine every day.
4. Creatinine is transported through the bloodstream to the kidneys. The kidneys filter out most of the creatinine and dispose of it in the urine.
Because the muscle mass in the body is relatively constant from day to day, the creatinine production normally remains essentially unchanged on a daily basis.