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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Crisaborole
Crisaborole
  • Crisaborole
  • Crisaborole
  • Crisaborole

Crisaborole

Price Get Latest Price
Package 1kg 25kg
Min. Order: 1kg
Supply Ability: 500kg
Update Time: 2025-12-25

Product Details

Product Name: Crisaborole CAS No.: 906673-24-3
Min. Order: 1kg Purity: 0.99
Supply Ability: 500kg Release date: 2025/12/25

Crisaborole (CAS 906673-24-3)?
?? ?ChemicalBook Product Profile?


?? ?Product Overview?

?Crisaborole? (C??H??BNO?) is a ?non-steroidal PDE4 inhibitor? with a molecular weight of ?251.05 g/mol?. This ?white crystalline powder? (≥99% purity, HPLC-validated) is FDA-approved for treating ?mild-to-moderate atopic dermatitis (AD)? in patients aged 2+ years?12. By inhibiting PDE4-mediated cytokine release, it reduces inflammation and itching without hormonal side effects. Available in ?1kg/5kg/25kg? sealed packaging with ?2-year stability? under dry, room-temperature storage?.

?Google Keywords?: Crisaborole CAS 906673-24-3, PDE4 Inhibitor API Supplier, Non-Hormonal Dermatitis Treatment, GMP-Certified Pharma Raw Material


? ?Key Advantages?

?? ?Non-Hormonal Safety?

  1. Zero systemic absorption | Ideal for pediatric and long-term use?12.
    ?? ?High Purity & Stability?

  2. ≥99% purity (HPLC/NMR validated) | Stable for ?2 years? under standard storage?34.
    ?? ?Targeted Efficacy?

  3. IC50 of ?0.49 μM for PDE4 inhibition? | Reduces TNF-α, IL-2, and IFN-γ cytokines?17.


?? ?Application Fields?

  • ?Dermatology?: Core API for topical ointments (e.g., 2% or 5% formulations) targeting AD and eczema?12.

  • ?Clinical Trials?: Key compound in anti-inflammatory drug development and pediatric AD research?37.

  • ?Global API Supply?: Bulk production for pharmaceutical manufacturers?45.


?? ?Quality Certifications?

  • ?Testing Methods?: HPLC, NMR, mass spectrometry, microbial limit testing?34.

  • ?Certifications?: ?GMP?, ?ISO 9001?, and ?ICH stability guidelines? compliance?25.


?? ?Market Trends?

The ?global atopic dermatitis market? is projected to reach ?$12.5 billion by 2030?, growing at ?7.8% CAGR?. Crisaborole holds ?15% of the PDE4 inhibitor segment?, with Asia-Pacific (China, India) leading API production and export?13.


?? ?Contact us for COA, bulk pricing, and custom synthesis!

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Company Profile Introduction

Wuhan Biocar Pharmaceutical Co., Ltd. is a high-tech and innovative enterprise specializing in the research, development, production, and sales of APIs and pharmaceutical intermediates (excluding finished drugs). Located in the heart of Optics Valley Biological City, our company leverages the cutting-edge facilities of the Wuhan University Scientific Research Laboratory and benefits from the region's favorable policies to advance the field of biomedicine. Guided by our business philosophy—"Driven by market demand, powered by technological innovation, and enabled by e-commerce"—we are committed to delivering biomedical products that are precise, high-quality, fast, and reliable. Our offerings serve pharmaceutical companies, university research institutions, hospital outpatient services, reagent providers, and distributors worldwide.

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