CRTH2-IN-1 NEW
| Price | $1820 | $2380 | $3100 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: CRTH2-IN-1 | CAS No.: 926661-54-3 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | CRTH2-IN-1 |
| Description | CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay. |
| In vitro | CRTH2-IN-1 (Ramatroban analog) is a new type of prostaglandin D2 receptor DP2 (CRTH2) antagonist with IC50 of 7 nM in human whole blood eosinophil deformation assay (hESC). It has efficacy in a mouse model of allergic rhinitis. Using 3H-PGD2 and human platelet membrane for human prostaglandin D1 receptor (hDP1) binding. Human thromboxane receptor (hTP) binding was performed using human platelet membrane and 3H-SQ-29,548. HIP / 293 membrane and 3Hiloprost were used for human prostacyclin receptor (hIP) binding. CRTH2-IN-1 inhibits hDP1 binding with IC50 of 1 μM. CRTH2-IN-1 inhibits the combination of hTP and hIP with IC50 greater than 100 μM. CRTH2-IN-1 inhibits human CYP subtypes CYP3A4, CYP 2C9 and CYP2D6 with IC50 of 7, 5 and> 30 μM, respectively. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | hDP2 | hDP1 | CYP3A4 | CYP 2C9 | CRTH2-IN-1 | CRTH-2-IN-1 | CRTH2IN1 | CRTH2 IN 1 |
| Inhibitors Related | Tebuconazole | Oxadiazon | Musk ketone | Naringin dihydrochalcone | Ipriflavone | Benzyl alcohol | Sudan IV | Naringin | Rebamipide | Dibenzothiophene | Clarithromycin | Memantine hydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $117.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-04-21 | |
| $2.00 |
VIP2Y
|
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2026-07-02 | |
| $3100.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-08-22 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY