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Postion:Product Catalog >CT52923
CT52923
  • CT52923

CT52923 NEW

Price $40 $82 $133
Package 10mg 25mg 50mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: CT52923 CAS No.: 205256-55-9
Purity: 99.92% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameCT52923
DescriptionCT52923 is a selective, orally active antagonist of platelet-derived growth factor receptor (PDGFR), functioning as an ATP-competitive inhibitor. It has versatile applications for researching pathological diseases such as atherosclerosis, glomerulonephritis, liver cirrhosis, pulmonary fibrosis, and cancer.
In vitroCT52923 inhibits PDGFRs and stem cell factor receptors with IC50 values of 100 to 200 nM. CT52923(0.01-30 μ M; 24 h) blocks smooth muscle cell migration or fibroblast proliferation induced by platelet-derived growth factor, IC50 is 64 and 280 nM respectively [1].
In vivoCT52923 (oral; 5,15,30 and 50 mg/kg; twice daily) significantly inhibits the formation of neointima after carotid artery injury in rats [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 60 mg/mL (128.33 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 2.5 mg/mL (5.35 mM), Sonication is recommended.
KeywordsPDGFR | CT-52923 | CT52923 | CT 52923
Inhibitors RelatedRegorafenib monohydrate | Sunitinib | Nintedanib | Imatinib Mesylate | Toceranib Phosphate | Sorafenib | Nintedanib esylate | Regorafenib | Lenvatinib mesylate | Lenvatinib | Pazopanib | Axitinib
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Angiogenesis related Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Anti-Fibrosis Compound Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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