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Postion:Product Catalog >CU-32
CU-32
  • CU-32

CU-32 NEW

Price $287 $987 $1680
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-20

Product Details

Product Name: CU-32 CAS No.: 2400954-16-5
Supply Ability: 10g Release date: 2026/04/20

Product Introduction

Bioactivity

NameCU-32
DescriptionCU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMF : 30 mg/mL (80.83 mM), Sonication is recommended.
DMSO : 30 mg/mL (80.83 mM), Sonication is recommended.
DMSO:PBS (pH 7.2) (1:5) : 0.16 mg/mL (0.43 mM), Sonication is recommended.
KeywordsCU-32 | CU32 | CU 32
Inhibitors Related2',3'-cGAMP sodium | HA-1004 dihydrochloride | RU.521 | G140 | G150 | 3'-Adenylic acid | 2',3'-cGAMP | IRAK4-IN-4 | PF-06928215 | HA-1004 | G108 | Decoyinine

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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