CAS:

MF:

MW:

Synonyms:

Product Categories:

Amino Acid Derivatives;

Peptide Compound

Application:

Antibiotic Research and Development: D-Ala-D-Ala is an important target in antibiotic research. Many antibiotics, such as beta-lactams (e.g., penicillin), work by binding to D-Ala-D-Ala residues found in the peptidoglycan layer of bacterial cell walls. By blocking the formation of these peptidoglycan cross-links, these antibiotics effectively disrupt the integrity of the bacterial cell wall, leading to cell death. Therefore, D-Ala-D-Ala serves as a crucial biomarker for the development and screening of new antibiotics.

Peptide Synthesis and Modification: D-Ala-D-Ala is often used as a building block in solid-phase peptide synthesis. Its specific stereochemistry and amino acid sequence allow for the controlled synthesis of peptides with desired biological activities. Additionally, D-Ala-D-Ala can be used as a substrate for enzymatic modifications or chemical conjugation reactions, enabling the introduction of functional groups or labels into peptides.

Biological Research and Diagnostics: The presence of D-Ala-D-Ala in bacterial cell walls can be exploited for diagnostic purposes. For example, antibodies or other molecular probes that specifically recognize D-Ala-D-Ala can be used to detect the presence of bacteria in clinical samples. This approach is particularly useful in the rapid diagnosis of bacterial infections.

Manufacturer:

Sichuan HongRi Pharm-Tech Co., Ltd.