一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Danirixin
Danirixin
  • Danirixin

Danirixin NEW

Price $56 $113 $189
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-20

Product Details

Product Name: Danirixin CAS No.: 954126-98-8
Purity: 99.78% Supply Ability: 10g
Release date: 2026/04/20

Product Introduction

Bioactivity

NameDanirixin
DescriptionDanirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
In vivoSystemic exposure following single doses of danirixin 10 mg, 25 mg, 50 mg, 100 mg, and 200 mg increased with increasing dose. Engagement of pharmacology was demonstrated as inhibition of ex-vivo CXCL1-induced CD11b expression on peripheral blood neutrophils when compared to placebo (approximately 50 % for 50 mg and 100 mg danirixin, and 72 % at 200 mg). There was a 37 % decrease in Cmax and a 16 % decrease in AUC (0-∞) following administration of danirixin in the presence of food. Cmax also decreased by 65 % when danirixin 100 mg was administered following omeprazole 40 mg once daily for 5 days [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 60 mg/mL (135.78 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween-80+45% Saline : 5 mg/mL (11.31 mM), Sonication is recommended.
KeywordsInhibitor | inhibit | GSK-1325756 | GSK 1325756 | Danirixin | CXCR2 | CXCR | CXC chemokine receptors
Inhibitors RelatedAZD8309 | rac-NBI-74330 | Tannic acid | Artemotil | CXCR2-IN-1 | Kynurenic acid | Soquelitinib | Plerixafor octahydrochloride | Tanimilast | 3-Indoleglyoxylic acid | Nicotinamide N-oxide | CXCL-CXCR1/2-IN-1
Related Compound LibrariesFailed Clinical Trials Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Infection Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$1.00
VIP7Y
Career Henan Chemical Co
2019-12-26

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY
嘉禾县| 漳平市| 合川市| 焦作市| 石柱| 龙里县| 礼泉县| 孟津县| 南岸区| 海南省| 远安县| 南充市| 太康县| 洞口县| 抚顺市| 成安县| 柳林县| 孟津县| 开江县| 福清市| 许昌县| 阿瓦提县| 宝应县| 阿瓦提县| 平武县| 慈利县| 彭水| 高碑店市| 广水市| 临夏市| 凤山市| 界首市| 漯河市| 太仆寺旗| 麻城市| 九龙坡区| 贺州市| 元阳县| 同德县| 安徽省| 绍兴县|