DAPTA NEW

Price	$40	$89	$155
Package	1mg	5mg	10mg

Supply Ability:	10g
Update Time:	2026-07-27

Product Details

Product Name: DAPTA	CAS No.: 106362-34-9
Purity: 100.00%	Supply Ability: 10g
Release date: 2026/07/27

Product Introduction

Bioactivity

Name	DAPTA
Description	DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.
In vitro	D-Ala-peptide T-amide (DAPTA), or Peptide T, named for its high threonine content (ASTTTNYT), is a synthetic peptide comprised of eight amino acids (185-192) of the gp120 V2 region and functions as a viral entry inhibitor by targeting selectively CCR5.?The anti-HIV-1 activity of DAPTA was evaluated in M/M infected with R5 HIV-1 strains.?DAPTA at 10(-9) M inhibited HIV-1 replication in M/M by > 90%.?PCR analysis of viral cDNA in M/M showed that DAPTA blocks HIV entry and in this way prevents HIV-1 infection.?Moreover, DAPTA acts as a strong inhibitor and was more active than the non-peptidic CCR5 antagonist TAK-779 in inhibiting apoptosis (mediated by RS HIV-1 strains produced and released by infected M/M) on a neuroblastoma cell line[1]
Storage	Keep away from moisture, Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 10 mM, Sonication is recommended.
Keywords	HIVProtease \| HIV Protease \| HIV \| DAPTA \| CCR5 \| CCR \| CC chemokine receptor
Inhibitors Related	Stavudine \| 5-Fluorouracil \| Emtricitabine \| Indole-2-carboxylic acid \| Dimethyl fumarate \| Lamivudine \| Valproic Acid \| (-)-Epigallocatechin Gallate \| Pirfenidone \| Decanedioic acid \| Dextran sulfate sodium salt (MW 5000) \| Bromhexine hydrochloride
Related Compound Libraries	Bioactive Compound Library \| Anti-Neurodegenerative Disease Compound Library \| Cytokine Inhibitor Library \| Membrane Protein-targeted Compound Library \| ReFRAME Related Library \| Drug Repurposing Compound Library \| Anti-Viral Compound Library \| Peptide Compound Library \| Inhibitor Library \| Immunology/Inflammation Compound Library \| Bioactive Compounds Library Max \| GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.