dBRD9 HCl NEW
| Price | $132 | $787 | $1070 |
| Package | 1mg | 25mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-09 |
Product Details
| Product Name: dBRD9 HCl | CAS No.: 2341840-98-8 |
| Purity: 99.57% | Supply Ability: 10g |
| Release date: 2026/06/09 |
Product Introduction
Bioactivity
| Name | dBRD9 HCl |
| Description | dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl does not degrade BRD4 or BRD7 at concentrations up to 5 μM. dBRD9 HCl displays antiproliferative effects in human AML cell lines. |
| In vitro | dBRD9 (0.5-5000 nM; 4 h) reduces the expression of BRD9 in MOLM-13 cells in a concentration dependent manner with no significant effect on the expression of actin, BRD4, and BRD7. dBRD9 (100 nM; 2 hours) exhibits selectivity towards BRD9 in MOLM-13 cells. dBRD9 (7 days) exhibits anti-proliferative effects on EOL-1 and MOML-13 cell lines [1]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 15.4 mg/mL (17.97 mM), Sonication is recommended. DMSO : 38.5 mg/mL (44.94 mM), Sonication is recommended. |
| Keywords | EpigeneticReaderDomain | Epigenetic Reader Domain | dBRD9 HCl | BRD9 |
| Inhibitors Related | ABBV-744 | SNDX-5613 | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | J-147 | 5-Ph-IAA | Bavdegalutamide | Curcumin | Naphthol AS-E | Vepdegestrant | JQ-1 (carboxylic acid) | Bisdemethoxycurcumin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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