DC-05 NEW
| Price | $64 | $156 | $263 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: DC-05 | CAS No.: 890643-16-0 |
| Purity: 99.94% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | DC-05 |
| Description | DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively). |
| In vitro | DC-05 is a non-nucleoside DNMT1 inhibitor with low micromolar IC50 values and significant selectivity toward other AdoMet-dependent protein methyltransferases.?DC-05 (1.25, 2.5, 5, and 10 μM) effectively inhibits the proliferation of HCT116 (human colon cancer) and Capan-1 (human pancreatic adenocarcinoma cells) after treatment for 24, 48, and 72 h. DC-05 displays poor potent activities against DNMT3A, DNMT3B, G9a, SUV39H1, MLL1, SET7/9, and PRMT1 (IC50: >200, >200, >150, >150, >150, >150, 37.1 μM) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (26.08 mM), Solution. DMSO : 250 mg/mL (651.91 mM), Sonication is recommended. 10% DMSO+90% Saline : < 10 mg/mL (26.08 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+90% Corn Oil : 3.3 mg/mL (8.61 mM), Sonication is recommended. |
| Keywords | PRMT1 | Inhibitor | inhibit | HistoneMethyltransferase | Histone Methyltransferase | DNMTs | DNMT1 | DNAMethyltransferase | DNA MTases | DNA methyltransferase (DNMT) | DNA Methyltransferase | DC-05 | DC05 | DC 05 |
| Inhibitors Related | MAK-683 hydrochloride | SNDX-5613 | Levetiracetam | Tazemetostat | Piribedil | XY1 | EPZ015666 | iso-Azalansta | CBHcy | γ-Oryzanol | MRTX-1719 | Hinokitiol |
| Related Compound Libraries | Reprogramming Compound Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Epigenetics Compound Library | Chromatin Modification Compound Library | Hematonosis Compound Library | Inhibitor Library | NO PAINS Compound Library | Stem Cell Differentiation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1980.00 |
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-05-21 | |
|
VIP6Y
|
XIAMEN SINOPEG BIOTECH CO., LTD.
|
2024-07-30 | ||
| $1980.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-04-20 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY