Deoxycorticosterone acetate NEW
| Price | $30 | $40 |
| Package | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: Deoxycorticosterone acetate | CAS No.: 56-47-3 |
| Purity: 99.19% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | Deoxycorticosterone acetate |
| Description | Deoxycorticosterone acetate (DOCA) is a steroid hormone produced by the adrenal glands, possessing mineralocorticoid activity and serving as a precursor to aldosterone. As an agonist of the mineralocorticoid receptor, DOCA can induce severe kidney damage, including inflammation, fibrosis, glomerular injury, and proteinuria. It is commonly used to establish animal models of chronic kidney injury and hypertension. |
| Kinase Assay | Kinase inhibition: The ability of compounds to inhibit ATR, ATM or DNAPK kinase activity istested using a radiometric-phosphate incorporation assay. A stock solution isprepared consisting of the appropriate buffer, kinase, and target peptide. To this isadded the compound of interest, at varying concentrations in DMSO to a final DMSO concentration of 7%. Assays are initiated by addition of an appropriate [γ-33P]ATP solution and incubated at 25 ℃. Assays are stopped, after the desired time course, by addition of phosphoric acid and ATP to a final concentration of 100 mM and 0.66 μM, respectively. Peptides are captured on a phosphocellulose membrane, prepared as per manufacturer's instructions, and washed six times with 200 μL of 100 mM phosphoric acid, prior to the addition of 100 μL of scintillation cocktail and scintillation counting on a 1450 Microbeta Liquid Scintillation Counter. Dose?response data are analyzed using GraphPad Prism software |
| Storage | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 13.47 mg/mL (36.16 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.68 mM), Sonication is recommended. Ethanol : 12.5 mg/mL (33.56 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | unilateral nephrectomy | renal inflammation | precursor | Mineralocorticoid Receptor | Inhibitor | inhibit | GlucocorticoidReceptor | Glucocorticoid Receptor | glomerular injury and proteinuria | fibrosis | EndogenousMetabolite | Endogenous Metabolite | DOC Acetate | DOC | Deoxycorticosterone Acetate | Deoxycorticosterone | Cortexone Acetate | Cortexone | aldosterone | adrenocortin | AdrenergicReceptor | Adrenergic Receptor | 11-Deoxycorticosterone Acetate | 11-Deoxycorticosterone |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | L-Cysteine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Guanidine thiocyanate | glycine | Malic acid | Glycerol | Thymidine | Gluconate Calcium |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Natural Product Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Bitter Compound library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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