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Postion:Product Catalog >Difamilast
Difamilast
  • Difamilast

Difamilast NEW

Price $63 $152 $247
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Difamilast CAS No.: 937782-05-3
Purity: 99.47% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameDifamilast
DescriptionDifamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).
In vitroDifamilast exerts inhibitory effects on PDE2[1].
In vivoIn relevant animal models of AD, Difamilast improves skin condition [3].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Corn Oil : 3.3 mg/mL (7.39 mM), Sonication is recommended.
DMSO : 100 mg/mL (223.99 mM), Sonication is recommended.
Keywordssubtype | phosphodiesterase-4 | Phosphodiesterase (PDE) | PDE4B | PDE4 | OPA-15406 | OPA15406 | OPA 15406 | Inhibitor | inhibit | Difamilast | dermatitis | atopic
Inhibitors RelatedBalipodect | Theophylline monohydrate | D(+)-Raffinose pentahydrate | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Sildenafil citrate | Doxofylline
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Pediatric Drug Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | FDA-Approved Drug Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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