Product Details
| Product Name: Diosmin | CAS No.: 520-27-4 |
| EC-No.: 208-289-7 | Min. Order: 1ton |
| Purity: 99% | Supply Ability: 1000T/M |
| Release date: 2025/11/04 |
Technical Data Sheet (TDS) – Diosmin
Product Name: Diosmin
Synonyms: 3′,5,7-Trihydroxy-4′-methoxyflavone-7-rhamnoglucoside
CAS No.: 520-27-4
Molecular Formula: C28H32O15
Molecular Weight: 608.54 g/mol
Grade: Food & Industrial Grade
Appearance: Yellow to light yellow crystalline powder
Odor & Taste: Characteristic, slightly bitter
1. Specifications
| Test Item | Specification | Method | Result (Typical) |
|---|---|---|---|
| Appearance | Yellow to light yellow crystalline powder | Visual | Light yellow crystalline powder |
| Odor & Taste | Characteristic, slightly bitter | Organoleptic | Characteristic, slightly bitter |
| Identification | Conforms to Diosmin standard | HPLC/IR/UV | Pass |
| Assay (Diosmin) | ≥ 95% (Food & Industrial) | HPLC | 98.2% |
| Solubility | Soluble in DMSO, slightly soluble in water | USP/Visual | Soluble in DMSO, slightly soluble in water |
| Loss on Drying | ≤ 1.0% | GB/T 5009.3 | 0.45% |
| Heavy Metals | ≤ 20 ppm | AAS/ICP-MS | 10 ppm |
| Lead (Pb) | ≤ 3 ppm | AAS/ICP-MS | 1 ppm |
| Arsenic (As) | ≤ 1 ppm | AAS/ICP-MS | < 0.5 ppm |
| Cadmium (Cd) | ≤ 1 ppm | AAS/ICP-MS | < 0.5 ppm |
| Mercury (Hg) | ≤ 0.1 ppm | AAS/ICP-MS | < 0.05 ppm |
| Total Plate Count | ≤ 1000 cfu/g | GB/T 4789.2 | 150 cfu/g |
| Yeast & Mold | ≤ 100 cfu/g | GB/T 4789.15 | 20 cfu/g |
| E. coli | Negative | GB/T 4789.3 | Negative |
| Salmonella | Negative | GB/T 4789.4 | Negative |
| Staphylococcus aureus | Negative | GB/T 4789.10 | Negative |
2. Physical & Chemical Properties
Melting Point: 269–271°C
pH (1% solution): 5.0 – 7.0
Density: ~1.5 g/cm3
Optical Rotation: [α]D20: +45° to +50° (c = 1, H2O)
Solubility: Practically insoluble in water, soluble in DMSO, slightly soluble in ethanol
3. Applications
Food Grade:
Nutritional supplements, functional foods, beverages
Supports vascular health and antioxidant properties
Industrial Grade:
Raw material for pharmaceutical formulations
Cosmetic and nutraceutical ingredient
Research chemical for flavonoid studies
4. Storage & Handling
Store in a cool, dry, and dark place
Keep container tightly closed
Protect from moisture and light
Shelf life: 2 years from manufacture date under recommended storage conditions
5. Safety
Non-toxic, non-irritant in normal handling
Use proper PPE when handling large quantities
Avoid inhalation of dust and contact with eyes
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- Address: C-309, No. 12 Yuzhou S. Rd, Haizhou, Lianyungang, Jiangsu, China

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