Dihydroxyproprofylline, also known as pantenidine and glycerofylline, is a derivative of xanthine drugs, similar to aminofylline, with bronchial dilation and coronary artery effect, but also strong heart and diuretic effect, but not as strong as aminofylline. It is mainly used to treat bronchial asthma, asthmatic bronchitis, pulmonary edema, cardiogenic edema, angina pectoris and so on. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor. May cause nausea, vomiting, headache, palpitation and other adverse reactions.

Appearance and properties: white powder

Density: 1.57g/cm3

Boiling point: 589.6oC at 760 mmHg

Melting point: 161-162 °C(lit.)

Flash point: 310.4oC

Refractive index: 1.5403 (172oC)

Water solubility: 33 g/100 mL (25 oC)

Stability: Stable under normal temperatures and pressures.

Storage conditions: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Vapor pressure: 9.57E-15mmHg at 25°C

Usage:Dihydroxyproprofylline smooth muscle relaxant, has bronchial dilation and coronary artery action, and has diuretic effect. Stable in gastric juices. Antiasthmatic effect is similar to aminophylline, especially suitable for accompanied by tachycardia.