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Postion:Product Catalog >Biochemical Engineering>Inhibitors>DM4
DM4
  • DM4

DM4 NEW

Price $31 $44 $72
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: DM4 CAS No.: 796073-69-3
Purity: 99.95% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameDM4
DescriptionDM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
In vitroDM4 is a cytotoxic maytansinoid drug and it is a structural analogue of maytansine. It also is a new thiol-containing and potent maytansinoid. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Which enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 99 mg/mL (126.86 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.23 mM), Sonication is recommended.
KeywordsMicrotubuleAssociated | Microtubule/Tubulin | Microtubule Associated | Inhibitor | inhibit | DM-4 | DM4 | DM 4 | ADCCytotoxin | ADC Payload | ADC Cytotoxin
Inhibitors RelatedMethotrexate | Flubendazole | Doxorubicin hydrochloride | Methotrexate disodium | 4-Isopropoxybenzoic acid | Dexamethasone acetate | Pregnenolone acetate | α-Cyclodextrin | Dexamethasone | Methylene Blue trihydrate | 4'-Demethylepipodophyllotoxin | Exatecan Mesylate
Related Compound LibrariesAnti-Lung Cancer Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Microtubule-Targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Clinical Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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