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Postion:Product Catalog >Biochemical Engineering>Inhibitors>DSM265
DSM265
  • DSM265

DSM265 NEW

Price $30 $64 $89
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: DSM265 CAS No.: 1282041-94-4
Purity: 99.79% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameDSM265
DescriptionDSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infections.
In vivoIn NOD-scid IL-2Rγnull (NSG) mice (23-36 g), DSM265 (0.5 - 75 mg/kg; oral administration; twice daily; for 4 days) exhibited potent antimalarial activity[2].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationH2O : < 0.1 mg/mL (insoluble.)
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.82 mM), Sonication is recommended.
Ethanol : 5 mg/mL (12.04 mM), Sonication is recommended.
DMSO : 30 mg/mL (72.23 mM), Sonication is recommended.
KeywordsPfDHODH | P. falciparum 3D7 parasites | P. falciparum | DSM-265 | DSM265 | DSM 265 | DHODH
Inhibitors RelatedFlubendazole | Kojic acid | Gum arabic | Urethane | Hydroxychloroquine | Metronidazole | Benzyl alcohol | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Methylene Blue trihydrate | Coumaran
Related Compound LibrariesFerroptosis Compound Library | Failed Clinical Trials Compound Library | Anti-Parasitic Compound Library | Mitochondrial Membrane Protein-Targeted Compound Library | Bioactive Compound Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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