DSO-5a NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: DSO-5a | CAS No.: 2195411-63-1 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | DSO-5a |
| Description | DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation. It is utilized in diabetes-related research [1]. |
| In vitro | DSO-5a (50 nM; 60min) induced IP-1 accumulation in hBB3-HEK cells with a pEC50 of 8.485 and elicited a potent calcium response with a pEC50 of 7.964 [1]. At 500 nM, it induced IP-1 accumulation in mBB3-HEK cells with a pEC50 of 7.262 and a calcium response with a pEC50 of 7.174 [1]. DSO-5a also activated ERK1/2 in both hBB3-H1299 and mBB3-HEK cells in a dose-dependent manner (0-100 nM) within 8 minutes [1]. |
| In vivo | DSO-5a (3-30 mg/kg; P.O.; 30 minutes) dose-dependently reduced glycemic variability in C57BL/6 mice [1], and at 10 mg/kg/day for 2-4 weeks, it lowered blood glucose levels in diabetic db/db mice [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | PHYTOL | Rosiglitazone | Urea | Gum arabic | Daidzein | Lactose | Magnesium acetate tetrahydrate | Maltitol | Gluconate Calcium | 2,3-Butanediol | NPC 15199 | Cloxiquine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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