DSRM-3716 NEW
| Price | $45 | $72 | $97 |
| Package | 50mg | 100mg | 200mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-15 |
Product Details
| Product Name: DSRM-3716 | CAS No.: 58142-99-7 |
| Purity: 97.28% | Supply Ability: 10g |
| Release date: 2026/07/15 |
Product Introduction
Bioactivity
| Name | DSRM-3716 |
| Description | Isoquinoline, 5-iodo- is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a metastable pool of damaged, but viable, axons. |
| In vitro | Treatment with the isoquinoline DSRM-3716produced dose-dependent inhibition of cADPR increase (IC50 = 2.8 μM) and substantial preservation of NAD+ in these cultures in a manner consistent with engagement and inhibition of SARM1 enzymatic NADase activity inside the cells. DSRM-3716prevented NfL release from severed axons in a dose-dependent manner[1]. |
| Storage | Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (7.84 mM), Sonication is recommended. DMSO : 38.46 mg/mL (150.79 mM), Sonication is recommended. 10% DMSO+90% Saline : 3.85 mg/mL (15.09 mM), Suspension. |
| Keywords | SARM1 | neurodegenerative | NADase | Inhibitor | inhibit | DSRM-3716 | DSRM3716 | DSRM 3716 | cADPR | axon | AndrogenReceptor | Androgen Receptor | 5-Iodoisoquinoline |
| Inhibitors Related | Dehydroisoandrosterone 3-acetate | 2-Ethylhexyl trans-4-methoxycinnamate | Hydroxychloroquine | Benzyl alcohol | Chloroquine phosphate | Enzalutamide | Chloranil | Thiamine hydrochloride | Testosterone propionate | 2-sec-Butylphenol | Flutamide | DHBP |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Prostate Cancer Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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