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Postion:Product Catalog >EGFR-IN-7
EGFR-IN-7
  • EGFR-IN-7

EGFR-IN-7 NEW

Price $98 $243 Get Latest Price
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-07-14

Product Details

Product Name: EGFR-IN-7 CAS No.: 2267329-76-8
Purity: 99.29% Supply Ability: 10g
Release date: 2026/07/14

Product Introduction

Bioactivity

NameEGFR-IN-7
DescriptionEGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.
In vitroTQB3804 displayed potent enzymatic activities for EGFRd746-750/T790M/C797S, EGFRL858R/T790M/C797S, EGFRd746-750/T790M, and EGFRL858R/T790M with IC50 of 0.46, 0.13, 0.26, and 0.19 nM respectively, and has similar enzymatic activity for EGFRWT (IC50 = 1.07) to Osimertinib. It also showed expected anti-proliferative activity in 4 cell lines, Ba/F3 (EGFRd746-750/T790M/C797S), NCI-H1975 (EGFRd746-750/T790M/C797S), PC9 (EGFRd746-750), and A431 (EGFRWT), with IC50 of 26.8, 163, 45, and 147 nM, respectively.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 0.71 mg/mL (1.02 mM), Sonication is recommended.
KeywordsTQB-3804 | TQB 3804 | Inhibitor | inhibit | HER1 | ErbB-1 | Epidermal growth factor receptor | EGFR-IN-7 | EGFRIN7 | EGFR(WT) | EGFR IN 7 | EGFR
Inhibitors Related(S)-Afatinib | Osimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Erlotinib hydrochloride | Erlotinib | Neratinib | Afatinib | Chalcone | Brigatinib | Genistein | Gefitinib
Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Anti-Lung Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | JAK-STAT Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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