Epsilon-V1-2 NEW
| Price | $61 | $147 | $263 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: Epsilon-V1-2 | CAS No.: 182683-50-7 |
| Purity: 97.09% | Supply Ability: 10g |
| Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | Epsilon-V1-2 |
| Description | Epsilon-V1-2 has been extensively investigated for its function as a PKC epsilon (PKCε) inhibitor. Epsilon-V1-2 has been widely applied in studies addressing ovarian aging, apoptosis in human granulosa cells, cerebral ischemia-reperfusion injury, brain development, hepatocyte insulin signaling, and neuronal cell death under ischemic conditions. Epsilon-V1-2 has been shown to effectively reduce PKCε activity, thereby enabling detailed exploration of regulatory pathways involving mitochondrial dynamics, calcium overload, AKT activation, brain atrophy, insulin resistance, and ferroptosis. Epsilon-V1-2 demonstrates notable therapeutic relevance in models of stroke, SHORT syndrome, hepatic steatosis, and brain injury, supporting its continued evaluation as a potential pharmacological agent across multiple disease contexts. |
| In vitro | Epsilon-V1-2 (1 μM, 24 hours) significantly inhibits OA-induced Cx43 Ser368 phosphorylation and protects myocardial gap junctions from OA-induced disruption [2]. |
| In vivo | Epsilon-V1-2 (20 mg/kg/day, subcutaneously implanted with 0.1 mL osmotic pump, administered daily for 4 weeks) significantly improved the beating score of transplanted FVB mouse hearts in C57BL/6J mice [3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100.00 mg/mL (118.49 mM), Sonication is recommended. H2O : ≥ 80 mg/mL, Sonication is recommended. |
| Keywords | Epsilon-V1-2 | Epsilon-V-1-2 | EpsilonV12 | Epsilon V1 2 |
| Inhibitors Related | PKN1/2-IN-1 | Forskolin | Darovasertib | Ellagic acid | α-Vitamin E | Ro-3306 | Staurosporine | Methyl-Hesperidin | Gondoic acid | Miltefosine | Fasudil hydrochloride | R59949 |
| Related Compound Libraries | Bioactive Compound Library | Kinase Inhibitor Library | Peptide Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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