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Postion:Product Catalog >ESI-08
ESI-08
  • ESI-08

ESI-08 NEW

Price $51 $122 $198
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-21

Product Details

Product Name: ESI-08 CAS No.: 301177-43-5
Purity: 99.05% Supply Ability: 10g
Release date: 2026/04/21

Product Introduction

Bioactivity

NameESI-08
DescriptionESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.
In vitroESI-08 (25 μM) does not alter cAMP-induced type I and II PKA holoenzymes activation while H89, a selective PKA inhibitor, blocked the type I or II PKA activities completely[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 50 mg/mL (141.45 mM), Sonication is recommended.
KeywordsRas | proteins | Inhibitor | inhibit | exchange | ESI-08 | ESI08 | ESI 08 | EPAC2 | EPAC1 | EPAC | cAMP
Inhibitors RelatedAdagrasib | BI-2493 | RMC-9805 | Bithionol | (R)-Naproxen | Ketoconazole | MRTX1133 | Sotorasib | RMC-7977 | Daraxonrasib | AMG410 | NMac1
Related Compound LibrariesFerroptosis Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Multi-Target Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | GPCR Compound Library | Anti-Cancer Compound Library | MAPK Inhibitor Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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