Everolimus is a derivative of sirolimus, also known as 40-O-(2-hydroxyethyl)-rapamycin, or 40-O-(2-hydroxyethyl)-sirolimus. It belongs to the kinase drugs that interfere with cell communication to prevent tumor cell growth. It is an oral mammalian rapamycin (mTOR) inhibitor. In the past, it was mainly used clinically to prevent rejection reactions after kidney transplantation and heart transplantation.

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