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Postion:Product Catalog >FAUC-365
FAUC-365
  • FAUC-365

FAUC-365 NEW

Price $48 $113 $172
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-26

Product Details

Product Name: FAUC-365 CAS No.: 474432-66-1
Purity: 99.62% Supply Ability: 10g
Release date: 2026/05/26

Product Introduction

Bioactivity

NameFAUC-365
DescriptionFAUC-365 is a D3 dopamine receptor agonist.
In vitroAs a dichloro derivative, FAUC-365 revealed D3 affinities that were comparable to its methoxy-substituted analogs, however, the selectivities of FAUC-365 against 5HT-1A, 5-HT2, and R1 were substantially higher, which was demonstrated by the extraordinary selectivity ratios of 17600, 7200, 5200, and 680 over D1, D2long, D2short, and D4, respectively, were determined for FAUC-365 with Ki of 0.50 nM. In addition, the benzothiophene analog FAUC 346 and its oxa analog showed partial agonist character with EC50 values at 0.36 and 1.5 nM, respectively [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationH2O : insoluble
DMSO : 50 mg/mL (108.12 mM), Sonication is recommended.
EtOH : insoluble
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.32 mM), Sonication is recommended.
KeywordsSPET | schizophrenia | Radioligand | Parkinson's disease | Inhibitor | inhibit | FAUC-365 | FAUC365 | FAUC 365 | DopamineReceptor | Dopamine Receptor | Dopamine | D3 receptor | D3
Inhibitors RelatedTrifluoperazine dihydrochloride | Clozapine N-Oxide | Mirtazapine | Hexamethonium Bromide | Butyrophenone | Octopamine hydrochloride | L-DOPA | Creatine | Dopamine hydrochloride | Oxolinic acid | Mianserin hydrochloride | Doxepin hydrochloride
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Anti-Alzheimer's Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Anti-Parkinson's Disease Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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