FD-IN-1 NEW
| Price | Get Latest Price |
| Package | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: FD-IN-1 | CAS No.: 1646682-14-5 |
| Purity: 98.85% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | FD-IN-1 |
| Description | FD-IN-1 (Compound 12) is an orally active Factor D (FD) inhibitor (IC50=12 nM) that also inhibits Factor XIa (FXIa) and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively. |
| In vitro | FD-IN-1 (Compound 12) shows activity in the alternative pathway (AP) functional inhibition assay: in an in vitro membrane attack complex (MAC) deposition test using 50% human whole blood (WB), its half-maximal inhibitory concentration (IC??) was found to be 0.26 μM[1]. |
| In vivo | At a dose of 10 mg/kg administered via oral gavage, FD-IN-1 fully inhibited the activity of the alternative pathway (AP) in human factor D knock-in mice, and this inhibitory effect was sustained for up to 10 hours[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 48 mg/mL (127.18 mM), Sonication is recommended. |
| Keywords | FD-IN-1 | FDIN1 | FD IN 1 |
| Inhibitors Related | Iptacopan hydrochloride | Heparin sodium salt | Dexamethasone acetate | Chymotrypsin | Dexamethasone | Apixaban | 2-Methoxyphenothiazine | Cyclosporin A | Dextran sulfate sodium salt (MW 5000) | 3-Phenoxybenzaldehyde | Coumarin | Benzamidine hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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