Febuxostat Acyl Glucuronide NEW
| Price | $890 |
| Package | 2500μg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Febuxostat Acyl Glucuronide | CAS No.: 1351692-92-6 |
| Purity: 98.00% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Febuxostat Acyl Glucuronide |
| Description | Febuxostat Acyl Glucuronide is the primary metabolite of the potent xanthine oxidase (XO) inhibitor Febuxostat. It is formed through the glucuronidation of the carboxylic acid group of Febuxostat, a process mediated by UDP-glucuronosyltransferase (UGT) enzymes. The production of this acyl glucuronide is a major elimination pathway for the parent drug. Researching this metabolite is essential for characterizing metabolic clearance, understanding drug-drug interactions, and evaluating the pharmacokinetic variability of Febuxostat across different patient populations, including those with UGT enzymatic polymorphisms. |
| In vitro | Febuxostat Acyl Glucuronide, primarily formed by UGT1A1/1A3/1A8/1A9, shows minimal XO inhibition, confirming glucuronidation as a major inactivation pathway. Due to its reactivity as an acyl glucuronide, it is studied for acyl migration and covalent protein binding to assess potential immunogenicity or toxicity [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Methanol : Soluble DMSO : Soluble |
| Inhibitors Related | H-ASP-PHE-OH | Allopurinol | 2-(Methylamino)benzoic acid | Melamine | Mycophenolate Mofetil | 10-Undecen-1-ol | Phytic acid dodecasodium salt hydrate | Baicalein | Isonicotinic acid | Urolithin A | Lansoprazole sulfide | 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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