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Postion:Product Catalog >API>Blood System Drugs>Haemostatic Drugs>Fibrinogen
Fibrinogen
  • Fibrinogen

Fibrinogen NEW

Price $40 $92
Package 100mg 500mg
Supply Ability: 10g
Update Time: 2026-07-27

Product Details

Product Name: Fibrinogen CAS No.: 9001-32-5
Supply Ability: 10g Release date: 2026/07/27

Product Introduction

Bioactivity

NameFibrinogen
DescriptionFibrinogen is a heterodimeric protein that can be cleaved by thrombin. Fibrinogen is a potential marker for cardiovascular disease and plays an important role in metabolism. Its absence can cause fibrinogenemia.
In vitroConfluent MVECs were serum starved for 16 h and incubated with one of the following: Fibrinogen (2 or 4 mg/ml), Fibrinogen (4 mg/ml) with antibody against ICAM-1 (50 μM), Fibrinogen (4 mg/ml) with antibodies against α5 and β1, or β3 integrins (50 μM each), or Fibrinogen (4 mg/ml) with MEK inhibitors PD98059 or U0126 (50 μM each) at 37°C for 30 min. Fibrinogen induced a distinct dose-dependent increase of ERK phosphorylation that was significantly decreased by the presence of MEK inhibitors, PD98059 or U0126. Treatment of ECs with PD98059 (0.44 ± 0.03 FIU/cell, n = 4) or U0126 (0.40 ± 0.02 FIU/cell, n = 4), did not alter ERK phosphorylation in ECs compared to that in the control group (0.50 ± 0.05 FIU/cell, n = 4). [1]
StorageKeep away from moisture,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
KeywordsNF-κB | NFκB | NF-kB | NFkB | Interleukin Related
Inhibitors RelatedKaolin | Chitin | D(+)-Raffinose pentahydrate | Triphenyl phosphate | Hydroxypropyl Cellulose | 1,8-Cineole | Ethyl linoleate | D-Psicose | 5-Aminosalicylic Acid | Zinc chloride | Gluconate Calcium | Gluconate sodium
Related Compound LibrariesBioactive Compound Library Plus

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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