Fluconazole NEW
| Price | $36 | $48 | $59 |
| Package | 50mg | 100mg | 200mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-19 |
Product Details
| Product Name: Fluconazole | CAS No.: 86386-73-4 |
| Purity: 98.57% | Supply Ability: 10g |
| Release date: 2026/05/19 |
Product Introduction
Bioactivity
| Name | Fluconazole |
| Description | Fluconazole (UK-49858) belongs to the triazole class of antifungal agents and is a CYP51 inhibitor (IC99 = 0.20–0.39 μg/mL against Candida albicans), possessing broad-spectrum antifungal activity, good oral absorption, and cell permeability. This compound is used for the treatment of various invasive fungal infections. |
| In vitro | Methods: The in vitro antifungal activity of Fluconazole against clinically isolated Candida species was determined by CLSI M27-E4 broth microdilution method, with incubation for 24-48 hours. Results: The MIC90 of Fluconazole against Candida albicans was 2 μg/mL, with a susceptibility rate of 92%; against Candida glabrata, the MIC90 was 16 μg/mL, with 98% showing dose-dependent susceptibility. The wild-type proportion of Fluconazole for recurrent VVC strains was significantly lower than other types (67% vs 77%).[1] Methods: Broth microdilution method was used to determine the in vitro activity of Fluconazole against Candida. YPD medium was used, with Fluconazole concentrations ranging from 0-128 μg/mL (two-fold dilutions), inoculation of 2×10^5 CFU/mL Candida, and incubation at 30°C for 24 hours before MIC reading. Results: Fluconazole showed good inhibitory effects against susceptible strains, but MIC values were significantly elevated against resistant strains.[2] |
| In vivo | Methods: A Galleria mellonella larval systemic infection model with Candida albicans was established. Fluconazole (20 μg/mL, 10 μL per larva, dissolved in DMSO) was administered by single injection 1.5-2 hours post-infection. Results: Fluconazole monotherapy significantly prolonged the median survival time of infected larvae (9.33 days vs 2.33 days) and reduced fungal burden.[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 30.6 mg/mL (99.91 mM), Sonication is recommended. DMSO : 260 mg/mL (848.92 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (6.53 mM), Sonication is recommended. |
| Keywords | UK49858 | UK 49858 | Triazole | kefyr | Inhibitor | inhibit | fungi,Candida | Fungal | Fluconazole | Candida | C. albicans | Antifungal | Antibiotic | albicans | Agent | 14-α Demethylase |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Benzyl propionate | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | ReFRAME Related Library | Anti-Fungal Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $36.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-05-19 | |
|
VIP1Y
|
Hefei Lbao Physical & Chemical Science Co.,Ltd
|
2025-11-20 | ||
|
VIP2Y
|
Shaanxi Xianhe Biotech Co., Ltd
|
2025-05-09 | ||
| $5.00 |
Wuhan JiyunZen Tech Co., Ltd.
|
2025-05-07 | ||
|
VIP6Y
|
RongNa Biotechnology Co.,Ltd
|
2025-04-29 | ||
|
VIP6Y
|
WUHAN FORTUNA CHEMICAL CO., LTD
|
2025-04-28 | ||
|
VIP2Y
|
Xi an Biohorlden Industry Trade Co Ltd
|
2025-04-11 | ||
| $120.00 |
Shandong Xuhuang New material CoLTD
|
2025-02-25 | ||
| $100.00 |
Hebei Yiduo Import and Export Co., Ltd.
|
2025-02-13 | ||
| $150.00 |
Hebei Zhuanglai Chemical Trading Co Ltd
|
2024-12-25 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY