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Postion:Product Catalog >API>Antineoplastic agents>Antimetabolites, Antineoplastic>Fludarabin
Fludarabin
  • Fludarabin
  • Fludarabin

Fludarabin NEW

Price $150
Package 1kg
Min. Order: 1kg
Supply Ability: 500kg
Update Time: 2025-05-23

Product Details

Product Name: Fludarabin CAS No.: 21679-14-1
Min. Order: 1kg Purity: 99%
Supply Ability: 500kg Release date: 2025/05/23

Product Description                                                       

 Name: Fludarabine
English synonym: 2-Fluoroadeninearabinoside
CAS Number: 21679-14-1
Molecular formula: C10H12FN5O4
Molecular weight: 285.23
EINECS number: 244-525-5

Function
This drug is a fluorinated nucleotide analogue of adenosine arabinose, which can relatively resist the deamination effect of adenosine deaminase. Fludarabin phosphate is rapidly dephosphorylated to form 2F ara-A, which can be taken up by cells and then phosphorylated by intracellular deoxycytidine kinase to form the active triphosphate chemicalbook salt 2F ara-ATP. This metabolite can be produced by inhibiting nucleotide reductase and DNA polymerase( α,δ and ε), DNA primers and DNA ligases inhibit DNA synthesis. In addition, it can partially inhibit RNA polymerase II, thereby reducing protein synthesis.
Application
Its phosphate group is rapidly cleaved in the bloodstream, and the remaining 2-fluoroadenosine (Fara-A) enters the cells and is phosphorylated into the active metabolite Farar ATP, exerting its effects. Used for chronic lymphocytic leukemia.


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Company Profile                                                           

Hebei Zhuanglai Chemical Trading Co.,Ltd. is a foreign trading company, specializing in developing and producing Chemical raw materials, pharmaceutical intermediates.It has its own factory, which procures itself a competitive edge in market.

For many years, our company has won many clients' support and trust because it always strives to make high-quality merchandise with favorable price. It commits itself to satisfy every clients, in return, our customer show great confidence and respect for our company. In spite of so many loyal customers won these years, Hegui keeps modest all the time and strives to better itself from every aspect.

We are looking forward to cooperating with you and having a win-win relationship with you. Please rest assured that we will satisfy you. Just feel free to contact me.

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Packing & Shipping                                                      

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FAQ                                                                                

Q1. What is your delivery term and delivery period?

We accept FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you. Competitive price with ready stocks; by Air within 7days, by sea within 14 days shipping after .


Q2. What's your main markets?

South&North America, Europe, Asia, Africa etc. Top customers among more than 80 countries; 30 years history; One-stop supplier.


Q3. What is the payment term? 

Normally we advise customers use Trade Assurance(is a free payment protection service for buyers is offered by Alibaba group), and we also receive T/T, Western Union or L/C.


Q4. Will you supply samples for test the quality?

We'd like to offer our customers samples for the quality evaluation for most products to develop business.




Company Profile Introduction

Hebei Zhuanglai Chemical Trading Co.,Ltd. is a foreign trading company, specializing in developing and producing Chemical raw materials, pharmaceutical intermediates.It has its own factory, which procures itself a competitive edge in market. For many years, our company has won many clients' support and trust because it always strives to make high-quality merchandise with favorable price. It commits itself to satisfy every clients, in return, our customer show great confidence and respect for our company. In spite of so many loyal customers won these years, Hegui keeps modest all the time and strives to better itself from every aspect. We are looking forward to cooperating with you and having a win-win relationship with you. Please rest assured that we will satisfy you. Just feel free to contact me.

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