一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Forodesine
Forodesine
  • Forodesine

Forodesine NEW

Price $59
Package 2mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: Forodesine CAS No.: 209799-67-7
Purity: 99.16% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameForodesine
DescriptionForodesine (BCX-1777) is an orally active and potent purine nucleoside phosphorylase (PNP) inhibitor, a new purine nucleoside analog, inhibitor of human lymphocyte proliferation, induces apoptosis in leukemic cells by increasing dGTP levels, and may be useful in the study of cutaneous T-cell lymphomas.
In vitroFormodicin (10-30 μM; 24 and 48 hours; RPMI-8226, MOLT-4 and 5T33MM cells) has no effect on MM cells at 24 hours, but decreases the percentage of viable cells in MOLT-4 cells by 40% [1]. Treatment with forodosine (10-30 μM; 24 and 48 h; RPMI-8226, MOLT-4 and 5T33MM cells) partially inhibited cell proliferation [1]. In the presence of 2'-deoxyguanosine (dGuo, 3-10 μM), fordifloxacin inhibits the proliferation of human lymphocytes activated by a variety of drugs such as interleukin-2 (IL-2), mixed lymphocyte reaction (MLR) and phytohemagglutinin (PHA) (IC50 values less than 0.1-0.38 μM) [2].
In vivoForodesine has excellent oral bioavailability (63%) in mice[2]. Forodesine(single dose of 10 mg/kg; in mice ) treatment, elevates dGuo to approximately 5 μM[2]. Forodesine is effective in prolonging the life span 2-fold or more, in the human peripheral blood lymphocyte severe combined immunodeficiency (hu-PBL-SCID) mouse model[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 80 mg/mL (300.47 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (12.39 mM), Sonication is recommended.
KeywordsRat PNP | Purine nucleoside phosphorylase | Mouse PNP | Monkey PNP | Human PNP | Forodesine | Dog PNP | BCX1777 | BCX 1777 | Apoptosis
Inhibitors RelatedStavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate
Related Compound LibrariesFailed Clinical Trials Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$15.00
Zhuozhou Wenxi import and Export Co., Ltd
2021-07-13
$15.00
Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY
襄樊市| 山西省| 宜都市| 襄汾县| 湘潭县| 临沧市| 慈利县| 辉县市| 孝昌县| 鹰潭市| 中西区| 九江县| 邮箱| 奉新县| 颍上县| 大荔县| 建水县| 垫江县| 阳泉市| 铜鼓县| 靖远县| 南郑县| 阜康市| 油尖旺区| 独山县| 治多县| 托克逊县| 永登县| 白河县| 桂阳县| 长垣县| 监利县| 诸暨市| 定南县| 舟山市| 北票市| 木兰县| 昭通市| 玉林市| 绥中县| 定安县|