Product Details
| Product Name:
FR901464 |
CAS No.:
146478-72-0 |
| Purity:
98.47% |
Supply Ability:
10g |
| Release date:
2026/04/21 |
Product Introduction
Bioactivity
| Name | FR901464 |
| Description | FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring. |
| In vitro | FR901464 (10-20 ng/ml; 6-24 hours) inhibited the growth of solid tumors, colon cancer, and methoxamine A fibrosarcoma in mice. FR901464 induced characteristic G1 and G2/M phase arrest in the cell cycle and internucleosomal degradation of genomic DNA in M-8 tumor cells by the same principle as SV40 promoter dependent cellular transcription. FR901464 (1-10 ng/ml) induced the transcription of some endogenous genes in M-8 cells, but did not inhibit the transcription of endogenous genes[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 90 mg/mL (177.3 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (6.5 mM), Sonication is recommended.
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| Keywords | FR901464 |
| Related Compound Libraries | Bioactive Compound Library | Rare Natural Product Library | Alkaloid Natural Product Library | Microbial Natural Product Library | Natural Product Library for HTS | Covalent Natural Product Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Suppliers |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States