G244-LM NEW
| Price | $44 | $98 | $178 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: G244-LM | CAS No.: 1563007-08-8 |
| Purity: 98.46% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | G244-LM |
| Description | G244-LM, a potent and specific inhibitor of tankyrase 1/2, effectively inhibits Wnt signaling. |
| In vitro | G244-LM is a potent and specific small-molecule tankyrase inhibitors, that reduce Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.?The novel tankyrase inhibitors completely block ligand-driven Wnt/β-catenin signaling in cell culture and display approximately 50% inhibition of APC mutation-driven signaling in most CRC cell lines.?It was previously unknown whether the level of AXIN protein stabilization by tankyrase inhibition is sufficient to impact tumor growth in the absence of normal APC activity. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 5 mM, Sonication is recommended. |
| Keywords | tankyrase1/2 | poly ADP ribose polymerase | PARP | Inhibitor | inhibit | G244-LM | G-244-LM | G244LM | G244 LM |
| Inhibitors Related | Chlorquinaldol | Urea | BGP-15 | Neohesperidin | 3-Aminobenzamide | Ethyl linoleate | Monensin sodium salt | Niraparib | AZ9482 | Olaparib | Benzamide | Methyl Vanillate |
| Related Compound Libraries | Glycometabolism Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $45.00 |
VIP2Y
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TargetMol Chemicals Inc.
|
2026-06-08 | |
|
VIP2Y
|
HEBEI RUIXIN ELECTRONIC NEW MATERIAL CO., LTD
|
2025-11-27 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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