Gadolinium chloride NEW
| Price | $53 | $82 |
| Package | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Gadolinium chloride | CAS No.: 10138-52-0 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Gadolinium chloride |
| Description | Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist |
| In vitro | Gadolinium chloride (GdCl ) , a well-known Kupffer/foam cell inhibitor, at late stages of NPC liver disease and compared it with NPC1 genetic rescue in hepatocytes in vivo.?GdCl treatment successfully blocked the endocytic capacity of hepatic Kupffer/foam measured by India ink endocytosis, decreased the levels CD68-A marker of Kupffer cells in the liver-and normalized the transaminase levels in serum of NPC mice to a similar extent to those obtained by genetic Npc1 rescue of liver cells.?Gadolinium salts are widely used as magnetic resonance imaging (MRI) contrasts.?This study opens the possibility of targeting foam cells with gadolinium or by other means for improving NPC liver disease.?Synopsis: Gadolinium chloride can effectively rescue some parameters of liver dysfunction in NPC mice and its potential use in patients should be carefully evaluated. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 7.5 mg/mL (28.45 mM), Sonication is recommended. Saline : >10 mg/mL, Solution. H2O : 9.85 mg/mL (37.37 mM), Sonication is recommended. |
| Keywords | specific | receptor | Inhibitor | inhibit | H9c2 | GdCl-3 | GdCl3 | GdCl 3 | Gadolinium Chloride | Gadolinium | CaSR | cardiovascular | Calcium-sensing receptor | calcium-sensing |
| Inhibitors Related | Upacicalcet | Strontium ranelate | γ-L-Glutamyl-L-alanine | Cinacalcet | TNCA | Tecalcet Hydrochloride | Strontium chloride | Calindol hydrochloride | Cinacalcet hydrochloride | AC265347 | γ-Glutamylvaline | Evocalcet |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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