Galidesivir triphosphate NEW
| Price | Get Latest Price |
| Package | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2025-08-22 |
Product Details
| Product Name: Galidesivir triphosphate | CAS No.: 1467740-78-8 |
| Supply Ability: 10g | Release date: 2025/08/22 |
Product Introduction
Bioactivity
| Name | Galidesivir triphosphate |
| Description | Galidesivir triphosphate is a substrate for viral RNA-dependent RNA polymerase (RDRP), resulting in termination of viral RNA replication and thus serves as an antiviral. Galidesivir triphosphate inhibits HCV NS5B RNA polymerase activity and protects mice against Ebola. Galidesivir triphosphate (Immucillin-A triphosphate) is converted by the prodrug Galidesivir. |
| In vitro | Galidesivir is converted to the mono-, di-, and triphosphates in virus-infected human Huh-7 cells.?Galidesivir triphosphate (Immucillin-A triphosphate) (1-60 μM) inhibits hepatitis C virus (HCV) RNA polymerase transcriptional activity in a cell-free, isolated enzyme transcription assay.The triphosphate is a substrate for viral RNA-dependent RNA polymerase.?Its incorporation permits the addition of a few additional encoded bases at which point the Galidesivir-modified RNA cannot be elongated.In virus-infected cells, Galidesivir is converted to the triphosphate, is incorporated into the viral transcript, and functions as an atypical chain-terminator for RNA-dependent RNA polymerases. |
| In vivo | In vivo conversion of Galidesivir to its TP (Galidesivir triphosphate) nucleotide is particularly efficient. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Immucillin-A Triphosphate | Immucillin-A | Galidesivir triphosphate | Galidesivir Triphosphate | Galidesivir | BCX-6870 | BCX 6870 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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