Gallic acid NEW
| Price | $38 |
| Package | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2025-05-02 |
Product Details
| Product Name: Gallic acid | CAS No.: 149-91-7 |
| Purity: 99.95% | Supply Ability: 10g |
| Release date: 2025/05/02 |
Product Introduction
Bioactivity
| Name | Gallic acid |
| Description | Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark. |
| Cell Research | Cell viability is measured using the MTT assay. PC12 cells are incubated at 37?C with Water2 or gallic acid at different concentrations for 24 h with or without pretreatment with resveratrol. They are then treated with the MTT solution (final concentration, 1 mg/mL) for 2 h. The dark-blue formazan crystals that formed in intact cells are dissolved in DMSO, and the absorbance at 570 nm is measured using a micro-ELISA reader.(Only for Reference) |
| In vitro | Gallic acid does not protect against H(2)O(2)-induced PC12 cell death. It reduced the viability of PC12 cells in a dose-dependent manner. Gallic acid also induces cleavage of poly (ADP-ribose) polymerase, which is strongly related to apoptosis in neurons. Gallic acid induces the phosphorylation of c-Jun N-terminal protein kinase (JNK) and the downregulation of Bcl-2 in PC12 cells. Gallic acid leads to a progressive reduction in the viability of vector-transfected PC12 cells, which is delayed in PC12 cells that overexpressed Bcl-2[2]. |
| In vivo | Gallic acid effectively protects rat erythrocytes. The antioxidant effect of the compound at the tested dosage in vivo was more prevalent than its prooxidative effects. Gallic acid has ameliorative effect on lipid peroxidation in vivo[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 7 mg/mL (41.15 mM), Sonication is recommended. Ethanol : 32 mg/mL (188.1 mM), Sonication is recommended. DMSO : 50 mg/mL (293.91 mM), Sonication is recommended. |
| Keywords | ROS | ReactiveOxygenSpecies | Reactive Oxygen Species | Gallic acid | Ferroptosis | EndogenousMetabolite | Endogenous Metabolite | COX | Apoptosis |
| Inhibitors Related | Sucrose | Stavudine | Daidzein | Guanidine hydrochloride | Fumaric acid | Tributyrin | Ferulic Acid | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Selected Plant-Sourced Compound Library | Miao medicine Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Antiparasitic Natural Product Library | Microbial Natural Product Library | Tobacco Monomer Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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