Glimepiride NEW
| Price | $52 |
| Package | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Glimepiride | CAS No.: 93479-97-1 |
| Purity: 98.87% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Glimepiride |
| Description | Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity. |
| In vitro | In both normal and insulin-resistant adipocytes, as well as in myocytes, Glimepiride effectively stimulates glucose transport, and the synthesis of lipids and glycogen. In cardiomyocytes, Glimepiride (IC50=6.8 nM) inhibits the pinacidil-activated whole-cell K(ATP) current. Additionally, in HEK 293 cells, Glimepiride (IC50=6.2 nM) blocks the K(ATP) channels formed by the co-expression of Kir6.2/SUR2A subunits. |
| In vivo | Within diabetic rats, Glimepiride has been shown to decrease the incidence of sperm abnormalities, enhance sperm count, and bolster antioxidant capacity. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 30 mg/mL (61.15 mM), Sonication is recommended. 10% DMSO+90% Corn Oil : 1.5 mg/mL (3.06 mM), Sonication is recommended. |
| Keywords | SUR2B | SUR2A | SUR1 | PotassiumChannel | Potassium Channel | Inhibitor | inhibit | HOE490 | HOE 490 | Glimepiride |
| Inhibitors Related | Benzenesulfonamide | Uridine 5'-monophosphate disodium salt | HEPPS | Hydrochlorothiazide | 1,8-Cineole | Tetraethylammonium bromide | 10-Undecenoic acid | Ursodeoxycholic acid | Chenodeoxycholic acid | 2,4-Di-tert-butylphenol | 2,2,2-Trichloroethanol | Indapamide |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bitter Compound library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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