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Postion:Product Catalog >GLPG0974
GLPG0974
  • GLPG0974

GLPG0974 NEW

Price $51 $122 $197
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-04-21

Product Details

Product Name: GLPG0974 CAS No.: 1391076-61-1
Purity: 99.80% Supply Ability: 10g
Release date: 2026/04/21

Product Introduction

Bioactivity

NameGLPG0974
DescriptionGLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.
In vitroGLPG0974 inhibits acetate-induced neutrophil migration strongly and inhibits CD11b activation-specific epitope [AE], a neutrophil-based pharmacodynamic marker, in a human whole blood assay[1].
In vivoGLPG0974(5 and 30 mg/kg; oral) exhibits good pharmacokinetic properties in rat with a bioavailability of 47% and dose-dependently increases the plasma exposure[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 257 mg/mL (529.91 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 5 mg/mL (10.31 mM), Sonication is recommended.
KeywordsGPR43 | GLPG0974 | GLPG 0974 | FFA2
Inhibitors RelatedMonomethyl fumarate | Kynurenic acid | Pamoic acid disodium | Azathioprine | CRTh2 antagonist 2 | Fezagepras sodium | Benzyl nicotinate | 1-methoxycyclopropanecarboxylic acid | TUG-1375 | CAY10595 | TUG-424 | Timapiprant
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Anhui Ruihan Technology Co., Ltd
2023-08-21

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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