Gly-β-MCA NEW
| Price | $199 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-09 |
Product Details
| Product Name: Gly-β-MCA | CAS No.: 66225-78-3 |
| Purity: 99.51% | Supply Ability: 10g |
| Release date: 2026/06/09 |
Product Introduction
Bioactivity
| Name | Gly-β-MCA |
| Description | Gly-β-MCA is an orally bioactive, enteroselective and potent inhibitor of the farnesoid X receptor (FXR), a bile acid, used in the study of obesity and diabetes. |
| In vitro | Gly-β-MCA is an effective intestinal selective farnesoid X receptor (FXR) inhibitor, belonging to the bile acids class[1]. Gly-β-MCA (Gly-MCA) exhibits resistance to hydrolysis by BSH (bile salt hydrolase)[1]. |
| In vivo | Gly-β-MCA (Gly-MCA, oral administration, 10 and 50 mg/kg) can prevent and treat diet-induced and genetic obesity, insulin resistance, and hepatic steatosis in mice, without causing systemic, hepatic, or intestinal toxicity[1].Gly-MCA does not increase fecal LCN-2 levels, indicating that Gly-MCA does not induce intestinal inflammation[1]. |
| Storage | Store at low temperature,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : <0.1 mg/mL (Insoluble) DMSO : 50 mg/mL (107.38 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.3 mM), Sonication is recommended. |
| Keywords | Gly-β-MCA | GlyβMCA | Gly-MCA | Gly-b-MCA | Gly-beta-MCA | Gly β MCA | FXR |
| Inhibitors Related | Stavudine | Aceglutamide | Hemin | Tamoxifen | Cysteamine hydrochloride | Guanidine hydrochloride | Hydroxychloroquine | Enzalutamide | Paeonol | Naringin | Alginic acid | Sildenafil citrate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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