GSK481 NEW
| Price | $43 | $71 | $131 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: GSK481 | CAS No.: 1622849-58-4 |
| Purity: 99.71% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | GSK481 |
| Description | GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death. |
| In vitro | GSK481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells. GSK481 has approximately equivalent RIP1 FP potencies against human and cynomolgus monkey RIP1 but was >100-fold less potent against nonprimate RIP[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : < 7.25 mg/mL (19.21 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 72.5 mg/mL (192.11 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) H2O : < 1 mg/mL (insoluble or slightly soluble) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 7.25 mg/mL (19.21 mM), Solution. |
| Keywords | RIPkinase | RIPK | RIP1 | RIP kinase | Receptor-interacting protein kinases | Inhibitor | inhibit | GSK-481 | GSK481 | GSK 481 |
| Inhibitors Related | PK68 | Necrostatin-1 | RIPK2-IN-5 | Oditrasertib | Apostatin-1 | LY-364947 | RIPK2-IN-3 | Necroptosis-IN-1 | ICCB-19 hydrochloride | Necrostatin-34 | RIPA-56 | GSK2983559 free acid |
| Related Compound Libraries | Bioactive Compound Library | Antidepressant Compound Library | Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | Pyroptosis Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Anti-Fibrosis Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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