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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Endocrinology & Hormones>GPR agonists>GW9508
GW9508
  • GW9508

GW9508 NEW

Price $29 $48 $78
Package 10mg 25mg 50mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: GW9508 CAS No.: 885101-89-3
Purity: 98.46% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameGW9508
DescriptionGW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
In vivoIn MIN6 cells, GW9508 stimulates insulin secretion in a dose-dependent manner and enhances insulin secretion mediated by KCl. In rat β-cells, GW9508 induces hyperpolarization and the opening of KATP channels. In HaCaT cells, GW9508 inhibits the expression of IL-11, IL-24, and IL-33 induced by TNF-α and IFN-γ. Additionally, in normal human epidermal keratinocytes, GW9508 suppresses the production of CCL5 and CXCL10.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationEthanol : 34.7 mg/mL (99.88 mM), Sonication is recommended.
10% DMSO+90% Saline : < 10 mg/mL (28.78 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (28.78 mM), Solution.
DMSO : 150 mg/mL (431.77 mM), Sonication is recommended.
KeywordsTNF-α | PotassiumChannel | Potassium Channel | KcsA | KATP | insulin | Inhibitor | inhibit | IFN-γ | GW-9508 | GW9508 | GPR40(FFA1) | GPR40 | GPR120 | glucose-sensitive | Free Fatty Acid Receptor | FFAR | FFA1 | CXCL10 | CCL5 | anti-inflammatory | anti-atherosclerotic
Inhibitors RelatedMinoxidil sulfate | Uridine 5'-monophosphate disodium salt | Tannic acid | Hydrochlorothiazide | 1,8-Cineole | Tetraethylammonium bromide | Ursodeoxycholic acid | Chenodeoxycholic acid | Minoxidil | 2,2,2-Trichloroethanol | Chlorzoxazone | Indapamide
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Neuroprotective Compound Library | NO PAINS Compound Library | Anti-Cardiovascular Disease Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | GPCR Compound Library | Anti-COVID-19 Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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