GX-585 NEW
| Price | $176 | $431 | $592 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-15 |
Product Details
| Product Name: GX-585 | CAS No.: 2098540-08-8 |
| Purity: 99.03% | Supply Ability: 10g |
| Release date: 2026/06/15 |
Product Introduction
Bioactivity
| Name | GX-585 |
| Description | GX-585 is a sulfonamide analog that is a Nav 1.7 channel inhibitor with analgesic activity for the study of neuropathic pain and inflammation. |
| In vitro | GX-585 is a potent inhibitor of NaV1.7 and highly selective for NaV1.5, but has different selectivity among neuronal NaV channels, with weaker inhibition of tetrodotoxin-resistant sodium currents in mouse DRG neurons, indicating weaker affinity for NaV1.8, with GX-585 blocking IC50 of 11.7 μM.[1] |
| In vivo | METHODS: In an animal model of acute injury, the effects of once daily (q.d.) oral administration of 3 mg/kg and 10 mg/kg GX-585 were evaluated 2 hours after the first, fifth, or twelfth daily dose. RESULTS: A single 10 mg/kg dose of GX-585 produced analgesic effects similar to repeated 3 mg/kg doses 2 hours after administration, but the activity was completely reversed after 24 hours. Thus, the long-term effects of repeated dosing are inconsistent with slow losses of the compound from plasma. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SodiumChannel | Sodium Channel | Olfr895-Agonist-10 | Olfr895Agonist10 | Olfr895 Agonist-10 | Olfr895 Agonist 10 | Nav1.7 channel | MDK-3673 | MDK 3673 | GX-585 |
| Inhibitors Related | Phenytoin sodium | Procaine | Ranolazine dihydrochloride | Tetracaine hydrochloride | Lidocaine | Safinamide | Permethrin | Valproic Acid | L-Aspartic aicd sodium | Lidocaine hydrochloride | Mebeverine hydrochloride | Dibucaine |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Sodium Channel Targeted Library | Neuroprotective Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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