Product Details
| Product Name:
HaloPROTAC3 |
CAS No.:
1799506-07-2 |
| Purity:
98.66% |
Supply Ability:
10g |
| Release date:
2026/05/14 |
Product Introduction
Bioactivity
| Name | HaloPROTAC3 |
| Description | HaloPROTAC3 (HaloPROTAC-3) is a conjugate of ligands for E3 and 16-atom-length linker and a degrader of HaloTag fusion proteins. |
| In vitro | HaloPROTAC 3 is an efficacious GFP-HaloTag7 degrader (DC50 = 19 nM). HaloPROTAC 3(625 nM) induces 90 % degradation of GFP-Halotag. HaloPROTAC 3 binds to VHL with an IC50 of 0.54 μM[1]. |
| Storage | Keep away from direct sunlight
Pure form: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.13 mM), Sonication is recommended.
DMSO : 83.14 mg/mL (104 mM), Sonication and heating are recommended.
|
| Keywords | VHL | LigandforE3Ligase | Ligand for E3 Ligase | HaloPROTAC3 |
| Inhibitors Related | Lenalidomide-Br | Pomalidomide 4'-alkylC3-acid | PT-179 | (S)-Thalidomide | Thalidomide | (S,R,S)-AHPC | Pomalidomide | Amino-PEG1-C2-acid | Lenalidomide | (S,R,S)-AHPC hydrochloride | 5-Aminothalidomide | Thalidomide 5-fluoride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Suppliers |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States